gwama

The GWAMA (Genome-Wide Association Meta Analysis) software, latest version 1.4, developed by WTCHG, is an invaluable tool in the Science Tools subcategory of Education. Available on Windows 7, 10, and 11, this freeware program allows users to conduct thorough meta-analyses of GWA studies for binary or quantitative phenotypes.

GWAMA is designed to carry out both fixed- and random-effect meta-analyses for genotyped and imputed SNPs. Estimates of the allelic odds ratio and 95% confidence interval are used for binary traits, while allelic effect size and standard error are utilized for quantitative phenotypes. The software is versatile, supporting various genetic models such as multiplicative, additive, dominant, and recessive. One of its standout features is the ability to highlight strand alignment errors and allele flipping through its robust error trapping facilities.

Moreover, GWAMA ensures the reliability of study results by performing tests of heterogeneity of effects between studies. This feature is crucial for researchers who need accurate analyses across different datasets. Users looking to download the latest iteration of this software can enjoy the capabilities and benefits for free.

When searching for keywords such as Genome-Wide Association Meta Analysis, meta-analysis of binary phenotypes, genetic models analysis software, and genomic meta-analysis tool, users will find GWAMA a prominent and reliable solution.

Pros:

• Comprehensive support for various genetic models.
• Error trapping facilities to prevent data inaccuracies.
• Free to download and use.

Cons:

• Limited to Windows operating systems.
• May present a steep learning curve for beginners in genomic studies.

You may want to check out more software, such as GenScn, Illusionae or Foucault, which might be related to gwama.