ProMass Deconvolution

ProMass Deconvolution is a cutting-edge science tool developed by Novatia, LLC. The latest version, 2.8, now offers completely automated ESI/LC/MS biomolecule charge deconvolution and web-based reporting. This specialized software is tailored for education purposes and runs seamlessly on Windows XP, Windows 7, Windows 10, and Windows 11. Among its many capabilities, ProMass for Xcalibur has been integrated into Thermo Scientific's Xcalibur data system, making it a versatile application for professionals and researchers alike.

Some standout features of the program include the automatic identification of terminal or internal fragments from oligonucleotide sequences, as well as support for identifying fragments from multiple oligo sequences, such as duplexes. Additionally, the software has enhanced functionalities for specifying modified oligonucleotides and support for "fuzzy" target masses, such as PTMs.

ProMass further impresses with its dynamic sorting of columns in web-based reports, allowing users to customize data presentation efficiently. The software permits specifying discrete retention time regions for spectral background subtraction and performs target mass purity estimation computed from deconvolution peak intensities and chromatogram area percentages. The ability to limit the number of deconvoluted spectra by chromatogram area percent or MS intensity helps streamline analysis. For ease of data handling, XML output is also supported. More

You may want to check out more software, such as PeakFit, CCDSharp or Topaz InFocus, which might be related to ProMass Deconvolution.