Downloading COM4 1.03 for Mac from the developer's website was possible when we last checked. We cannot confirm if there is a free download of this app available. This free Mac app is an intellectual property of LTE IB UNICAMP.
Please check the Mac app with an antivirus before launch as it is downloaded from the developer's website, and we cannot ensure that it is safe. The program is included in Education Tools. The following version: 1.0 is the most frequently downloaded one by the program users.
From the developer:
COM4 is an app that simulates oxygen consumption by isolated mitochondria. Also, substrate combinations and inhibitors can be simulated. COM simulates functional information obtained from isolated mitochondria. Simulations results are shown in two graphs.
You may want to check out more Mac applications, such as MacSpice, Periodic Table or RAAViewer, which might be related to COM4.