You could have downloaded HYPHY 2.1 for Mac from our application library for free. The bundle identifier for HYPHY for Mac is org.hyphy. This free Mac application is an intellectual property of Sergei L Kosakovsky Pond. HYPHY for Mac is categorized as Education Tools. The most popular version among the application users is 2.0.
From the developer:
HyPhy is an open-source software package for the analysis of genetic sequences using techniques in phylogenetics, molecular evolution, and machine learning. It features a complete graphical user interface (GUI) and a rich scripting language for limitless customization of analyses.
You may want to check out more software for Mac, such as Genealogy Pro, Curvus Pro X or Analytics to Earth, which might be similar to HYPHY.