Downloading Monolix-s 2016.0 for Mac from the developer's website was possible when we last checked. We cannot confirm if there is a free download of this app available. The application lies within Education Tools, more precisely Science. The actual developer of this software for Mac is Lixoft. Please check the Mac app with an antivirus before launch as it is downloaded from the developer's website, and we cannot ensure that it is safe.
From the developer:
Monolix is a simple solution for non-linear mixed effects modeling (NLME) for pharmacometrics. It is based on the SAEM algorithm and provides robust, global convergence even for complex PK/PD models. Monolix is used for preclinical and clinical population PK/PD modeling and for Systems Pharmacology.
You may want to check out more software for Mac, such as ScienceMatrix, Enzyme X or CUDA, which might be related to Monolix-s.