Access a molecular design environment to create models and simulations of small molecules and macromolecules, search for and view information about chemical compounds, perform calculations to identify and optimize lead molecules, and process structure-activity data to predict the level of biological activity or potency.
SYBYL-X 2.1.1 was available to download from the developer's website when we last checked. We cannot confirm if there is a free download of this software available. The most popular versions of the SYBYL-X are 2.1, 2.0 and 1.3. We recommend checking the downloaded files with any free antivirus. This software is a product of Tripos. The software relates to Education Tools. This PC software is suitable for 32-bit and 64-bit versions of Windows XP/7/8/10/11.
From the developer:
SYBYL-X is a program that enables you to find new lead candidates, optimize lead series or perform other related life science experiments like modeling a protein structure. The program has capabilities for small molecule modeling and simulation, macromolecular modeling and simulation, cheminformatics, lead identification and lead optimization.
You may want to check out more software, such as SRIM, EarthBrowser or Solmetric SunEye, which might be similar to SYBYL-X.